Intermediate susceptibility to ciprofloxacin among Salmonella enterica serovar Typhi isolates in Lima, Peru.

نویسندگان

  • Coralith García
  • Veerle Lejon
  • Gertrudis Horna
  • Lizeth Astocondor
  • Raymond Vanhoof
  • Sophie Bertrand
  • Jan Jacobs
چکیده

Thirty-three Salmonella enterica serovar Typhi blood isolates from Lima, Peru (2008 to 2012), were fully susceptible to trimethoprim-sulfamethoxazole, chloramphenicol, ceftriaxone, and tetracycline; 8/33 (24.2%) showed intermediate susceptibility to ciprofloxacin carrying mutations in the quinolone resistance-determining region of the gyrA gene (Ser83-Phe and Asp87-Asn) and in the gyrB gene (Ser464-Phe).

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Intermediate susceptibility to ciprofloxacin among Salmonella Typhi isolates, Lima, Peru

16 Thirty-three Salmonella Typhi blood isolates from Lima, Peru (2008-2012), were fully 17 susceptible to trimethoprim-sulfamethoxazole, chloramphenicol, ceftriaxone, and 18 tetracycline; 8/33 (24.2%) showed intermediate susceptibility to ciprofloxacin carrying 19 mutations in the quinolone resistance-determining region of the gyrA gene (Ser83-Phe and 20 Asp87-Asn); and in the gyrB gene (Ser464...

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Molecular characterization of ciprofloxacin-resistant Salmonella enterica serovar Typhi and Paratyphi A causing enteric fever in India.

OBJECTIVES To define the genetic characteristics and resistance mechanisms of clinical isolates of Salmonella enterica serovar Typhi (S. Typhi) and S. enterica serovar Paratyphi A (S. Paratyphi A) exhibiting high-level fluoroquinolones resistance. METHODS Three S. Typhi and two S. Paratyphi A ciprofloxacin-resistant isolates (MICs > 4 mg/L) were compared with isolates with reduced susceptibil...

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عنوان ژورنال:
  • Journal of clinical microbiology

دوره 52 3  شماره 

صفحات  -

تاریخ انتشار 2014